Isotopically Labeled Compounds
Cayman Chemical -AbscIsIc AcId-d6 1mg
An internal standard for the quantification of (+)-abscisic acid by GC- or LC-MS
Apexbio Technology LLC A-TOCOPHEROL D6-1mg
-Tocopherol-d6 (CAS No 113892-08-3) is a deuterated form of vitamin E primarily used in biomedical research to study the antioxidant properties of tocopherols Originating from synthetic processes this compound plays a crucial role in research focused on oxidative stress lipid peroxidation and associated cellular pathways Its mechanism of action involves scavenging free radicals and modulating enzymatic activity related to reactive oxygen species In vitro studies typically report -Tocopherol-d6 activity in nanomolar to low micromolar ranges making it suitable for exploring cellular antioxidative responses Common applications include use in cell models such as hepatocytes or neural cells and in animal studies assessing oxidative damage and protective mechanisms It is also employed in drug screening to evaluate the efficacy of antioxidant therapies Experimental concentrations typically depend on the specific research design
Cambridge Isotope Laboratories 80% Ethylene glycol 20% DMSO-D6 1 5mm tube
80% Ethylene glycol 20% DMSO-D6 1 5mm tube
Cambridge Isotope Laboratories Methanol-D4 (D 99 8%) 0 05% v/v TMS 25 g
Methanol-D4 (D 99 8%) 0 05% v/v TMS 25 g
Medchemexpress LLC 1-pyrrolidine-2,2,3,3,4,4-d6-acetamide, α-ethyl-5-oxo-, (αS)- | 1133229-30-7 | MFCD08063556 | 98.7% | 176.25 g/mol | C8H8D6N2O2 | 5 MG
Levetiracetam-d6 (ring-d6) is a deuterated analog of levetiracetam used as an internal standard and tracer for quantitative analysis of levetiracetam in biological matrices. It supports accurate isotope-dilution measurements and is provided with analytical documentation for laboratory assays.
- High deuterium incorporation to minimize isotopic interference.
- Suitable for LC-MS, GC-MS, and NMR quantitative assays.
- Purity 98.7% as determined by LC-MS.
- Molecular weight 176.25 g/mol and formula C8H8D6N2O2 for unambiguous identification.
- Supplied with certificate of analysis and product data sheet.
- Intended for use as an internal standard in biological sample analysis.
Cambridge Isotope Laboratories ACETONE (13C3, 99%), 1 G, 93628-01-4
ACETONE (13C3, 99%), 1 G, 93628-01-4
Cambridge Isotope Laboratories Sodium Deuteroxide (D) 30% in D2O | 14014-06-3 | MFCD00037669 | 50 g
Sodium Deuteroxide (D) 30% in D2O | Purity: 99.5% | Mol Wt: 41 | 14014-06-3 | MFCD00037669 | 50 g
Medchemexpress LLC Mexiletine-d6 hydrochloride | 1329835-60-0 | 99.9% | C11H12D6ClNO | 1 MG
Mexiletine-d6 hydrochloride is a deuterium labeled Mexiletine hydrochloride. It acts as a Class IB antiarrhythmic and a non-selective voltage-gated sodium channel blocker.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D18 | 2230218-36-5 | 98.79% | C21H28N6 | 25 MG
D18 is an immune modulator and TLR7/8 dual agonist, enhancing PD-L1 expression via epigenetic regulation to increase tumor sensitivity to PD-1/PD-L1 blockade. It also serves as an ADC cytotoxin, exhibiting strong immune activation and anti-tumor activity, frequently used in cancer research, especially for colon cancer.
- Functions as a TLR7/8 dual agonist (EC50 = 24 nM for hTLR7, 10 nM for hTLR8).
- Increases tumor sensitivity to PD-1/PD-L1 blockade.
- Exhibits strong immune activation and anti-tumor activity.
- Frequently employed in cancer research, particularly for colon cancer.
- Elevates IFN-γ, TNF-α, IL-1β, IL-12 p40, and IP-10 in hPBMCs (in vitro).
- Inhibits tumor growth in BALB/c mice bearing CT26 tumors (in vivo).
- Increases immune cell penetration.
- Demonstrates good safety.
Cambridge Isotope Laboratories 16 ALPHA-HYDROXYESTRONE (2,3,4-13C3,99%), 0.25 MG, 1241684-28-5
16 ALPHA-HYDROXYESTRONE (2,3,4-13C3,99%), 0.25 MG, 1241684-28-5
Cambridge Isotope Laboratories L-ASCORBIC ACID (1-13C, 99%), 0.1 G, 178101-88-7
L-ASCORBIC ACID (1-13C, 99%), 0.1 G, 178101-88-7
Cambridge Isotope Laboratories 25-Hydroxyvitamin D2 (26 26 26 27 27 27-D6 96%) CP 95% 1 mg
25-Hydroxyvitamin D2 (26 26 26 27 27 27-D6 96%) CP 95% 1 mg